Tell us a little more about the format of your podcasts. Here are some questions that would help us help you:

  • How many people will be in the studio at the same time?
  • Why did you select the PR40?
  • Why did you select the Presonus 16.4.2?
  • How many Skype guests do you expect to have at the same time?
  • Are you likely going to need a headphone amplifier?
  • Do you understand the difference between balanced and unbalanced connections?

It sounds like you're going about this the right way. That's a good equipment list. If I were you, I might consider saving some money on the microphone, but that's a matter of preference. For a boom, don't try to get an isolating boom. Get a shock mount for the mic. Atlas makes the best booms, IMHO. You will need some specialized cables and, in all probability, some ground loop isolators. (Take a look at that ART T8.)